Impaired apoptotic cell clearance in CGD due to altered macrophage programming is reversed by phosphatidylserine-dependent production of IL-4

Chronic granulomatous disease (CGD) is characterized by overexuberant inflammation and autoimmunity that are attributed to deficient anti-inflammatory signaling. Although regulation of these processes is complex, phosphatidylserine (PS)–dependent recognition and removal of apoptotic cells (efferocyt...

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Autores principales: Fernandez-Boyanapalli, Ruby F., Frasch, S. Courtney, McPhillips, Kathleen, Vandivier, R. William, Harry, Brian L., Riches, David W. H., Henson, Peter M., Bratton, Donna L.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Hematology 2009
Materias:
Phagocytes, Granulocytes, and Myelopoiesis
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2651016/
https://ncbi.nlm.nih.gov/pubmed/18952895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-05-160564
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