Evaluation Of Ires-Mediated, Cell Type-Specific Cytotoxicity Of Poliovirus Using A Colorimetric Cell Proliferation Assay

PVS-RIPO is a recombinant oncolytic poliovirus designed for clinical application to target CD155 expressing malignant gliomas and other malignant diseases. PVS-RIPO does not replicate in healthy neurons and is therefore non-pathogenic in rodent and non-human primate models of poliomyelitis. A tetraz...

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Detalhes bibliográficos
Main Authors: Yang, Xiaoyi, Chen, Eying, Jiang, Hengguang, Muszynski, Karen, Harris, Raymond D., Giardina, Steven L., Gromeier, Matthias, Mitra, Gautam, Soman, Gopalan
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2650828/
https://ncbi.nlm.nih.gov/pubmed/18951922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jviromet.2008.09.020
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