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Two Separate Interfaces between the Voltage Sensor and Pore Are Required for the Function of Voltage-Dependent K(+) Channels

Voltage-dependent K(+) (Kv) channels gate open in response to the membrane voltage. To further our understanding of how cell membrane voltage regulates the opening of a Kv channel, we have studied the protein interfaces that attach the voltage-sensor domains to the pore. In the crystal structure, th...

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Autors principals: Lee, Seok-Yong, Banerjee, Anirban, MacKinnon, Roderick
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2650729/
https://ncbi.nlm.nih.gov/pubmed/19260762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1000047
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