Virologic Failure in Therapy-Naïve Subjects on Aplaviroc plus Lopinavir-Ritonavir: Detection of Aplaviroc Resistance Requires Clonal Analysis of Envelope

The CCR100136 (EPIC) study evaluated the antiviral activity of the novel CCR5 entry inhibitor aplaviroc in combination with lopinavir-ritonavir in drug-naïve human immunodeficiency virus type 1-infected subjects. Although the trial was stopped prematurely due to idiosyncratic hepatotoxicity, 11 subj...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Kitrinos, Kathryn M., Amrine-Madsen, Heather, Irlbeck, David M., Word, J. Michael, Demarest, James F.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2009
Materias:
Antiviral Agents
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2650553/
https://ncbi.nlm.nih.gov/pubmed/19075068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01057-08
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares