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Virological and Pharmacological Parameters Predicting the Response to Lopinavir-Ritonavir in Heavily Protease Inhibitor-Experienced Patients

The genotypic inhibitory quotient (GIQ) has been proposed as a way to integrate drug exposure and genotypic resistance to protease inhibitors and can be useful to enhance the predictivity of virologic response for boosted protease inhibitors. The aim of this study was to evaluate the predictivity of...

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Hauptverfasser: Marcelin, Anne-Geneviève, Cohen-Codar, Isabelle, King, Martin S., Colson, Philippe, Guillevic, Emmanuel, Descamps, Diane, Lamotte, Claire, Schneider, Véronique, Ritter, Jacques, Segondy, Michel, Peigue-Lafeuille, Hélène, Morand-Joubert, Laurence, Schmuck, Anne, Ruffault, Annick, Palmer, Pierre, Chaix, Marie-Laure, Mackiewicz, Vincent, Brodard, Véronique, Izopet, Jacques, Cottalorda, Jacqueline, Kohli, Evelyne, Chauvin, Jean-Pierre, Kempf, Dale J., Peytavin, Gilles, Calvez, Vincent
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2005
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1087618/
https://ncbi.nlm.nih.gov/pubmed/15855487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.5.1720-1726.2005
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