Expression, purification and preliminary diffraction studies of CmlS

CmlS, a flavin-dependent halogenase (FDH) present in the chloramphenicol-biosynthetic pathway in Streptomyces venezuelae, directs the dichlorination of an acetyl group. The reaction mechanism of CmlS is of considerable interest as it will help to explain how the FDH family can halogenate a wide rang...

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Hlavní autoři: Latimer, Ryan, Podzelinska, Kateryna, Soares, Alexei, Bhattacharya, Anupam, Vining, Leo C., Jia, Zongchao, Zechel, David L.
Médium: Artigo
Jazyk:Inglês
Vydáno: International Union of Crystallography 2009
Témata:
Crystallization Communications
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2650468/
https://ncbi.nlm.nih.gov/pubmed/19255478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309108043091
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