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Stimulated nuclear translocation of NF-κB and shuttling differentially depend on dynein and the dynactin complex

Translocation from the cytoplasm to the nucleus is required for the regulation of gene expression by transcription factors of the nuclear factor kappa B (NF-κB) family. The p65:p50 NF-κB heterodimer that predominates in many cell types can undergo stimulated movement, following degradation of the Iκ...

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Autori principali: Shrum, Cynthia K., DeFrancisco, Daniel, Meffert, Mollie K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2650318/
https://ncbi.nlm.nih.gov/pubmed/19196984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0806677106
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