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The cardiac glycoside binding site on the Na,K-ATPase α2 isoform plays a role in the dynamic regulation of active transport in skeletal muscle

The physiological significance of the cardiac glycoside-binding site on the Na,K-ATPase remains incompletely understood. This study used a gene-targeted mouse (α2(R/R)) which expresses a ouabain-insensitive α2 isoform of the Na,K-ATPase to investigate whether the cardiac glycoside-binding site plays...

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Detalhes bibliográficos
Main Authors: Radzyukevich, T. L., Lingrel, J. B, Heiny, J. A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2650304/
https://ncbi.nlm.nih.gov/pubmed/19196986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0804150106
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