Phospholemman is not required for the acute stimulation of Na(+)-K(+)-ATPase α(2)-activity during skeletal muscle fatigue

The Na(+)-K(+)-ATPase α(2)-isoform in skeletal muscle is rapidly stimulated during muscle use and plays a critical role in fatigue resistance. The acute mechanisms that stimulate α(2)-activity are not completely known. This study examines whether phosphorylation of phospholemman (PLM/FXYD1), a regul...

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Detalhes bibliográficos
Publicado no:Am J Physiol Cell Physiol
Main Authors: Manoharan, Palanikumar, Radzyukevich, Tatiana L., Hakim Javadi, Hesamedin, Stiner, Cory A., Landero Figueroa, Julio A., Lingrel, Jerry B, Heiny, Judith A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4683216/
https://ncbi.nlm.nih.gov/pubmed/26468207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00205.2015
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