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The highly conserved cardiac glycoside binding site of Na,K-ATPase plays a role in blood pressure regulation

The Na,K-ATPase contains a binding site for cardiac glycosides, such as ouabain, digoxin, and digitoxin, which is highly conserved among species ranging from Drosophila to humans. Although advantage has been taken of this site to treat congestive heart failure with drugs such as digoxin, it is unkno...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Dostanic-Larson, Iva, Van Huysse, James W., Lorenz, John N., Lingrel, Jerry B
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: National Academy of Sciences 2005
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1276084/
https://ncbi.nlm.nih.gov/pubmed/16243970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0507358102
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