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Principal determinants leading to transition state formation of a protein–protein complex, orientation trumps side-chain interactions
The binding transition state (TS) is the rate-limiting step for transient molecular interactions. This important step in the molecular recognition process, however, is largely understood only at a qualitative level. To establish a more quantitative picture of the TS structure, we exploit a set of bi...
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| Huvudupphovsmän: | , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
National Academy of Sciences
2009
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2650303/ https://ncbi.nlm.nih.gov/pubmed/19196954 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0809800106 |
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