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Chromosomal location targets different MYC family gene members for oncogenic translocations

The MYC family of cellular oncogenes includes c-Myc, N-myc, and L-myc, which encode transcriptional regulators involved in the control of cell proliferation and death. Accordingly, these genes become aberrantly activated and expressed in specific types of cancers. For example, c-Myc translocations o...

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Autors principals: Gostissa, Monica, Ranganath, Sheila, Bianco, Julia M., Alt, Frederick W.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2650145/
https://ncbi.nlm.nih.gov/pubmed/19174520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0812763106
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