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Role of Syk in B-cell development and antigen-receptor signaling

Antigen receptors (BCRs) on developing B lymphocytes play two opposing roles—promoting survival of cells that may later bind a foreign antigen and inhibiting survival of cells that bind too strongly to self-antigens. It is not known how these opposing outcomes are signaled by BCRs on immature B cell...

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Библиографические подробности
Главные авторы: Cornall, Richard J., Cheng, Alex M., Pawson, Tony, Goodnow, Christopher C.
Формат: Artigo
Язык:Inglês
Опубликовано: The National Academy of Sciences 2000
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC26501/
https://ncbi.nlm.nih.gov/pubmed/10677523
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