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Role of the Syk autophosphorylation site and SH2 domains in B cell antigen receptor signaling

To explore the mechanism(s) by which the Syk protein tyrosine kinase participates in B cell antigen receptor (BCR) signaling, we have studied the function of various Syk mutants in B cells made Syk deficient by homologous recombination knockout. Both Syk SH2 domains were required for BCR-mediated Sy...

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Bibliografiske detaljer
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 1995
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2192262/
https://ncbi.nlm.nih.gov/pubmed/7500027
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