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Role of the Syk autophosphorylation site and SH2 domains in B cell antigen receptor signaling
To explore the mechanism(s) by which the Syk protein tyrosine kinase participates in B cell antigen receptor (BCR) signaling, we have studied the function of various Syk mutants in B cells made Syk deficient by homologous recombination knockout. Both Syk SH2 domains were required for BCR-mediated Sy...
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| Format: | Artigo |
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| Langue: | Inglês |
| Publié: |
The Rockefeller University Press
1995
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2192262/ https://ncbi.nlm.nih.gov/pubmed/7500027 |
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