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Airway glutathione homeostasis is altered in children with severe asthma: Evidence for oxidant stress

BACKGROUND: Severe asthma is characterized by persistent airway inflammation and increased formation of reactive oxygen species. OBJECTIVES: Glutathione (GSH) is an important antioxidant in the epithelial lining fluid (ELF). We hypothesized that airway GSH homeostasis was altered in children with se...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Fitzpatrick, Anne M., Teague, W. Gerald, Holguin, Fernando, Yeh, Mary, Brown, Lou Ann S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2649685/
https://ncbi.nlm.nih.gov/pubmed/19130935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2008.10.047
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