FcγRIII and FcγRIV are indispensable for acute glomerular inflammation induced by switch variant monoclonal antibodies

The relative ability of IgG subclasses to cause acute inflammation, and the roles of specific effector mechanisms in this process is not clear. We explored this in an in vivo model of glomerular inflammation in the mouse. TNP was planted on the glomerular basement membrane after conjugation to nephr...

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Hoofdauteurs: Giorgini, Angela, Brown, Heather J., Lock, Helen R., Nimmerjahn, Falk, Ravetch, Jeffrey V., Verbeek, J. Sjef, Sacks, Steven H., Robson, Michael G.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2008
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2649421/
https://ncbi.nlm.nih.gov/pubmed/19050295
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