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Understanding the Association of Apolipoprotein E4 with Alzheimer Disease: Clues from Its Structure

Despite intense interest, the molecular mechanisms underlying the association of apoE4 with Alzheimer disease are not clear. Because the function (or dysfunction) of a protein is based on its structure, this review focuses on the effects of the structural differences among the isoforms on neurodegen...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Zhong, Ning, Weisgraber, Karl H.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2009
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2649104/
https://ncbi.nlm.nih.gov/pubmed/18948255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R800009200
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