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Understanding the Association of Apolipoprotein E4 with Alzheimer Disease: Clues from Its Structure
Despite intense interest, the molecular mechanisms underlying the association of apoE4 with Alzheimer disease are not clear. Because the function (or dysfunction) of a protein is based on its structure, this review focuses on the effects of the structural differences among the isoforms on neurodegen...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Biochemistry and Molecular Biology
2009
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2649104/ https://ncbi.nlm.nih.gov/pubmed/18948255 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R800009200 |
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