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Regulation of Reactive Oxygen Species Homeostasis by Peroxiredoxins and c-Myc

Peroxiredoxins (Prxs) are highly conserved proteins found in most organisms, where they function primarily to scavenge reactive oxygen species (ROS). Loss of the most ubiquitous member of the family, Prx1, is associated with the accumulation of oxidatively damaged DNA and a tumor-prone phenotype. Pr...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Graves, J. Anthony, Metukuri, Mallikarjuna, Scott, Donald, Rothermund, Kristi, Prochownik, Edward V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2649099/
https://ncbi.nlm.nih.gov/pubmed/19098005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M807564200
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