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Regulation of Reactive Oxygen Species Homeostasis by Peroxiredoxins and c-Myc

Peroxiredoxins (Prxs) are highly conserved proteins found in most organisms, where they function primarily to scavenge reactive oxygen species (ROS). Loss of the most ubiquitous member of the family, Prx1, is associated with the accumulation of oxidatively damaged DNA and a tumor-prone phenotype. Pr...

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Autors principals: Graves, J. Anthony, Metukuri, Mallikarjuna, Scott, Donald, Rothermund, Kristi, Prochownik, Edward V.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2649099/
https://ncbi.nlm.nih.gov/pubmed/19098005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M807564200
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