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Asymmetric Synthetic Access to the Hetisine Alkaloids: Total Synthesis of (+)-Nominine

A dual cycloaddition strategy for the synthesis of the hetisine alkaloids has been developed, illustrated by a concise asymmetric total synthesis of (+)-nominine (7). The approach relies on an early-stage intramolecular 1,3-dipolar cycloaddition of a 4-oxido-isoquinolinium betaine dipole with an ene...

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Détails bibliographiques
Auteurs principaux: Peese, Kevin M., Gin, David Y.
Format: Artigo
Langue:Inglês
Publié: 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2648811/
https://ncbi.nlm.nih.gov/pubmed/18046691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.200701290
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