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A recombination execution checkpoint regulates the choice of homologous recombination pathway during DNA double-strand break repair

A DNA double-strand break (DSB) is repaired by gene conversion (GC) if both ends of the DSB share homology with an intact DNA sequence. However, if homology is limited to only one of the DSB ends, repair occurs by break-induced replication (BIR). It is not known how the homology status of the DSB en...

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Hlavní autoři: Jain, Suvi, Sugawara, Neal, Lydeard, John, Vaze, Moreshwar, Tanguy Le Gac, Nicolas, Haber, James E.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2009
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2648549/
https://ncbi.nlm.nih.gov/pubmed/19204116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1751209
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