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Robust production and passaging of infectious HPV in squamous epithelium of primary human keratinocytes
Using Cre-loxP-mediated recombination, we established a highly efficient and reproducible system that generates autonomous HPV-18 genomes in primary human keratinocytes (PHKs), the organotypic raft cultures of which recapitulated a robust productive program. While E7 promoted S-phase re-entry in num...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2648537/ https://ncbi.nlm.nih.gov/pubmed/19131434 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1735109 |
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