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Cell Type-Specific Induction and Inhibition of Apoptosis by Herpes Simplex Virus Type 2 ICP10

Herpes simplex virus (HSV) inhibits apoptosis induced by external stimuli in epithelial cells. In contrast, apoptosis is the primary outcome in HSV-infected lymphocytes. Here, we show that HSV type 2 (HSV-2) gene expression appears to be necessary for the induction of apoptosis in Jurkat cells, a T-...

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Détails bibliographiques
Auteurs principaux: Han, Jin-Young, Miller, Sara A., Wolfe, Teresa M., Pourhassan, Hoda, Jerome, Keith R.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 2009
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2648263/
https://ncbi.nlm.nih.gov/pubmed/19116254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02088-08
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