Herpes Simplex Virus Type 1 ICP0 Protein Does Not Accumulate in the Nucleus of Primary Neurons in Culture

Infected-cell protein 0 (ICP0), the product of the herpes simplex virus (HSV) immediate-early (IE) α0 gene, is a promiscuous transactivator of viral early (E) and late (L) gene expression. HSV mutants lacking ICP0 function are severely deficient in viral growth and protein synthesis, particularly at...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Chen, Xiao-Ping, Li, Jia, Mata, Marina, Goss, James, Wolfe, Darren, Glorioso, Joseph C., Fink, David J.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2000
Assuntos:	Virus-Cell Interactions
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC102052/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11024142/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.21.10132-10141.2000
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