Herpes Simplex Virus Type 1 ICP0 Protein Does Not Accumulate in the Nucleus of Primary Neurons in Culture

Infected-cell protein 0 (ICP0), the product of the herpes simplex virus (HSV) immediate-early (IE) α0 gene, is a promiscuous transactivator of viral early (E) and late (L) gene expression. HSV mutants lacking ICP0 function are severely deficient in viral growth and protein synthesis, particularly at...

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Autores principales: Chen, Xiao-Ping, Li, Jia, Mata, Marina, Goss, James, Wolfe, Darren, Glorioso, Joseph C., Fink, David J.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2000
Materias:
Virus-Cell Interactions
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC102052/
https://ncbi.nlm.nih.gov/pubmed/11024142
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