An HLA-A2-Restricted T-Cell Epitope Mapped to the BNLF2a Immune Evasion Protein of Epstein-Barr Virus That Inhibits TAP

The early lytic cycle protein of Epstein-Barr virus (EBV), BNLF2a, has recently been shown to play a critical role in immune evasion by inhibiting the peptide transporter associated with antigen processing (TAP), thereby blocking antigen-specific CD8(+) T-cell recognition of many lytic cycle antigen...

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Auteurs principaux: Bell, Melissa J., Abbott, Rachel J. M., Croft, Nathan P., Hislop, Andrew D., Burrows, Scott R.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 2009
Sujets:
Pathogenesis and Immunity
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2648255/
https://ncbi.nlm.nih.gov/pubmed/19129449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01724-08
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