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Allosteric Coupling between the Lid and Interdomain Linker in DnaK Revealed by Inhibitor Binding Studies

The molecular chaperone DnaK assists protein folding and refolding, translocation across membranes, and regulation of the heat shock response. In Escherichia coli, the protein is a target for insect-derived antimicrobial peptides, pyrrhocoricins. We present here the X-ray crystallographic analysis o...

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Bibliografiske detaljer
Main Authors: Liebscher, Markus, Roujeinikova, Anna
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2648196/
https://ncbi.nlm.nih.gov/pubmed/19103929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01131-08
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