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Allosteric Coupling between the Lid and Interdomain Linker in DnaK Revealed by Inhibitor Binding Studies

The molecular chaperone DnaK assists protein folding and refolding, translocation across membranes, and regulation of the heat shock response. In Escherichia coli, the protein is a target for insect-derived antimicrobial peptides, pyrrhocoricins. We present here the X-ray crystallographic analysis o...

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Detalhes bibliográficos
Main Authors: Liebscher, Markus, Roujeinikova, Anna
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2648196/
https://ncbi.nlm.nih.gov/pubmed/19103929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01131-08
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