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Endochondral ossification is required for hematopoietic stem cell niche formation

Little is known about the formation of niches, local micro-environments required for stem cell maintenance. Here we develop an in vivo assay for adult hematopoietic stem cell (HSC) niche formation 1-2. With this assay, we identified a population of progenitor cells with surface markers CD45(-)Tie2(-...

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Dettagli Bibliografici
Autori principali: Chan, Charles K. F., Chen, Ching-Cheng, Luppen, Cynthia A., Kraft, Daniel L., Kim, Jae-Beom, DeBoer, Anthony, Wei, Kevin, Weissman, Irving L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2648141/
https://ncbi.nlm.nih.gov/pubmed/19078959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature07547
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