Epigenetic and in vivo comparison of diverse MSC sources reveals an endochondral signature for human hematopoietic niche formation

In the last decade there has been a rapid expansion in clinical trials using mesenchymal stromal cells (MSCs) from a variety of tissues. However, despite similarities in morphology, immunophenotype, and differentiation behavior in vitro, MSCs sourced from distinct tissues do not necessarily have equ...

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Veröffentlicht in:Blood
Hauptverfasser: Reinisch, Andreas, Etchart, Nathalie, Thomas, Daniel, Hofmann, Nicole A., Fruehwirth, Margareta, Sinha, Subarna, Chan, Charles K., Senarath-Yapa, Kshemendra, Seo, Eun-Young, Wearda, Taylor, Hartwig, Udo F., Beham-Schmid, Christine, Trajanoski, Slave, Lin, Qiong, Wagner, Wolfgang, Dullin, Christian, Alves, Frauke, Andreeff, Michael, Weissman, Irving L., Longaker, Michael T., Schallmoser, Katharina, Majeti, Ravindra, Strunk, Dirk
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2015
Schlagworte:
Hematopoiesis and Stem Cells
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4287636/
https://ncbi.nlm.nih.gov/pubmed/25406351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-04-572255
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