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Inference of haplotypic phase and missing genotypes in polyploid organisms and variable copy number genomic regions

BACKGROUND: The power of haplotype-based methods for association studies, identification of regions under selection, and ancestral inference, is well-established for diploid organisms. For polyploids, however, the difficulty of determining phase has limited such approaches. Polyploidy is common in p...

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Autori principali: Su, Shu-Yi, White, Jonathan, Balding, David J, Coin, Lachlan JM
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2647950/
https://ncbi.nlm.nih.gov/pubmed/19046436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-9-513
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