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FACT facilitates chromatin transcription by RNA polymerases I and III

Efficient transcription elongation from a chromatin template requires RNA polymerases (Pols) to negotiate nucleosomes. Our biochemical analyses demonstrate that RNA Pol I can transcribe through nucleosome templates and that this requires structural rearrangement of the nucleosomal core particle. The...

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Bibliographic Details
Main Authors: Birch, Joanna L, Tan, Bertrand C-M, Panov, Kostya I, Panova, Tatiana B, Andersen, Jens S, Owen-Hughes, Tom A, Russell, Jackie, Lee, Sheng-Chung, Zomerdijk, Joost C B M
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2009
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2647773/
https://ncbi.nlm.nih.gov/pubmed/19214185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.33
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