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UBF activates RNA polymerase I transcription by stimulating promoter escape

Ribosomal RNA gene transcription by RNA polymerase I (Pol I) is the driving force behind ribosome biogenesis, vital to cell growth and proliferation. The key activator of Pol I transcription, UBF, has been proposed to act by facilitating recruitment of Pol I and essential basal factor SL1 to rDNA pr...

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Bibliographic Details
Main Authors: Panov, Kostya I, Friedrich, J Karsten, Russell, Jackie, Zomerdijk, Joost C B M
Format: Artigo
Language:Inglês
Published: 2006
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1523182/
https://ncbi.nlm.nih.gov/pubmed/16858408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601221
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