c-di-GMP is an Effective Immunomodulator and Vaccine Adjuvant Against Pneumococcal Infection

Cyclic diguanylate (c-di-GMP) is a unique bacterial intracellular signaling molecule capable of stimulating enhanced protective innate immunity against various bacterial infections. The effects of intranasal pretreatment with c-di-GMP, or intraperitoneal coadministration of c-di-GMP with the pneumol...

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Main Authors: Ogunniyi, Abiodun D., Paton, James C., Kirby, Alun C., McCullers, Jonathan A., Cook, Jan, Hyodo, Mamoru, Hayakawa, Yoshihiro, Karaolis, David K. R.
格式: Artigo
語言:Inglês
出版: 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2647696/
https://ncbi.nlm.nih.gov/pubmed/18640167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2008.06.099
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