Hidden abnormalities and novel classification of t(15;17) acute promyelocytic leukemia (APL) based on genomic alterations

Acute promyelocytic leukemia (APL) is a hematopoietic malignant disease characterized by the chromosomal translocation t(15;17), resulting in the formation of the PML-RARA gene. Here, 47 t(15;17) APL samples were analyzed with high-density single-nucleotide polymorphism microarray (50-K and 250-K SN...

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Autores principales: Akagi, Tadayuki, Shih, Lee-Yung, Kato, Motohiro, Kawamata, Norihiko, Yamamoto, Go, Sanada, Masashi, Okamoto, Ryoko, Miller, Carl W., Liang, Der-Cherng, Ogawa, Seishi, Koeffler, H. Phillip
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Hematology 2009
Materias:
Myeloid Neoplasia
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2647673/
https://ncbi.nlm.nih.gov/pubmed/19109227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-12-130260
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