Prevalence and prognostic impact of allelic imbalances associated with leukemic transformation of Philadelphia chromosome–negative myeloproliferative neoplasms

Philadelphia chromosome–negative myeloproliferative neoplasms (MPNs) including polycythemia vera, essential thrombocythemia, and primary myelofibrosis show an inherent tendency for transformation into leukemia (MPN-blast phase), which is hypothesized to be accompanied by acquisition of additional ge...

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Auteurs principaux: Thoennissen, Nils H., Krug, Utz O., Lee, Dhong Hyun Tony, Kawamata, Norihiko, Iwanski, Gabriela B., Lasho, Terra, Weiss, Tamara, Nowak, Daniel, Koren-Michowitz, Maya, Kato, Motohiro, Sanada, Masashi, Shih, Lee-Yung, Nagler, Arnon, Raynaud, Sophie D., Müller-Tidow, Carsten, Mesa, Ruben, Haferlach, Torsten, Gilliland, D. Gary, Tefferi, Ayalew, Ogawa, Seishi, Koeffler, H. Phillip
Format: Artigo
Langue:Inglês
Publié: American Society of Hematology 2010
Sujets:
Myeloid Neoplasia
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2854432/
https://ncbi.nlm.nih.gov/pubmed/20068225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-07-235119
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