Prevalence and prognostic impact of allelic imbalances associated with leukemic transformation of Philadelphia chromosome–negative myeloproliferative neoplasms

Philadelphia chromosome–negative myeloproliferative neoplasms (MPNs) including polycythemia vera, essential thrombocythemia, and primary myelofibrosis show an inherent tendency for transformation into leukemia (MPN-blast phase), which is hypothesized to be accompanied by acquisition of additional ge...

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Main Authors: Thoennissen, Nils H., Krug, Utz O., Lee, Dhong Hyun Tony, Kawamata, Norihiko, Iwanski, Gabriela B., Lasho, Terra, Weiss, Tamara, Nowak, Daniel, Koren-Michowitz, Maya, Kato, Motohiro, Sanada, Masashi, Shih, Lee-Yung, Nagler, Arnon, Raynaud, Sophie D., Müller-Tidow, Carsten, Mesa, Ruben, Haferlach, Torsten, Gilliland, D. Gary, Tefferi, Ayalew, Ogawa, Seishi, Koeffler, H. Phillip
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Hematology 2010
Assuntos:
Myeloid Neoplasia
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2854432/
https://ncbi.nlm.nih.gov/pubmed/20068225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-07-235119
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