Tumor Necrosis Factor Promotes Runx2 Degradation through Up-regulation of Smurf1 and Smurf2 in Osteoblasts

Tumor necrosis factor (TNF) plays an important role in the pathogenesis of inflammatory bone loss through stimulation of osteoclastic bone resorption and inhibition of osteoblastic bone formation. Compared with the well established role of TNF in osteoclastogenesis, mechanisms by which TNF inhibits...

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Bibliografiset tiedot
Päätekijät: Kaneki, Hiroyuki, Guo, Ruolin, Chen, Di, Yao, Zhenqiang, Schwarz, Edward M., Zhang, Ying E., Boyce, Brendan F., Xing, Lianping
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2005
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2647592/
https://ncbi.nlm.nih.gov/pubmed/16373342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M509430200
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