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Phylogenomics of DNA topoisomerases: their origin and putative roles in the emergence of modern organisms

Topoisomerases are essential enzymes that solve topological problems arising from the double-helical structure of DNA. As a consequence, one should have naively expected to find homologous topoisomerases in all cellular organisms, dating back to their last common ancestor. However, as observed for o...

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Bibliografiske detaljer
Main Authors: Forterre, Patrick, Gadelle, Danièle
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2647321/
https://ncbi.nlm.nih.gov/pubmed/19208647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp032
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