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Effects of magnesium and related divalent metal ions in topoisomerase structure and function

The catalytic steps through which DNA topoisomerases produce their biological effects and the interference of drug molecules with the enzyme–DNA cleavage complex have been thoroughly investigated both from the biophysical and the biochemical point of view. This provides the basic structural insight...

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Bibliografske podrobnosti
Main Authors: Sissi, Claudia, Palumbo, Manlio
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2647314/
https://ncbi.nlm.nih.gov/pubmed/19188255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp024
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