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Pseudocounts for transcription factor binding sites
To represent the sequence specificity of transcription factors, the position weight matrix (PWM) is widely used. In most cases, each element is defined as a log likelihood ratio of a base appearing at a certain position, which is estimated from a finite number of known binding sites. To avoid bias d...
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| Main Authors: | , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Oxford University Press
2009
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2647310/ https://ncbi.nlm.nih.gov/pubmed/19106141 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn1019 |
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