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Pseudocounts for transcription factor binding sites

To represent the sequence specificity of transcription factors, the position weight matrix (PWM) is widely used. In most cases, each element is defined as a log likelihood ratio of a base appearing at a certain position, which is estimated from a finite number of known binding sites. To avoid bias d...

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Bibliografische gegevens
Hoofdauteurs: Nishida, Keishin, Frith, Martin C., Nakai, Kenta
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2009
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2647310/
https://ncbi.nlm.nih.gov/pubmed/19106141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn1019
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