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PSI-BLAST pseudocounts and the minimum description length principle

Position specific score matrices (PSSMs) are derived from multiple sequence alignments to aid in the recognition of distant protein sequence relationships. The PSI-BLAST protein database search program derives the column scores of its PSSMs with the aid of pseudocounts, added to the observed amino a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Altschul, Stephen F., Gertz, E. Michael, Agarwala, Richa, Schäffer, Alejandro A., Yu, Yi-Kuo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2647318/
https://ncbi.nlm.nih.gov/pubmed/19088134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn981
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