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PSI-BLAST pseudocounts and the minimum description length principle
Position specific score matrices (PSSMs) are derived from multiple sequence alignments to aid in the recognition of distant protein sequence relationships. The PSI-BLAST protein database search program derives the column scores of its PSSMs with the aid of pseudocounts, added to the observed amino a...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2647318/ https://ncbi.nlm.nih.gov/pubmed/19088134 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn981 |
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