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PSI-BLAST pseudocounts and the minimum description length principle

Position specific score matrices (PSSMs) are derived from multiple sequence alignments to aid in the recognition of distant protein sequence relationships. The PSI-BLAST protein database search program derives the column scores of its PSSMs with the aid of pseudocounts, added to the observed amino a...

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Bibliografiska uppgifter
Huvudupphovsmän: Altschul, Stephen F., Gertz, E. Michael, Agarwala, Richa, Schäffer, Alejandro A., Yu, Yi-Kuo
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2009
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2647318/
https://ncbi.nlm.nih.gov/pubmed/19088134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn981
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