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PSI-BLAST pseudocounts and the minimum description length principle

Position specific score matrices (PSSMs) are derived from multiple sequence alignments to aid in the recognition of distant protein sequence relationships. The PSI-BLAST protein database search program derives the column scores of its PSSMs with the aid of pseudocounts, added to the observed amino a...

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Bibliografiske detaljer
Main Authors: Altschul, Stephen F., Gertz, E. Michael, Agarwala, Richa, Schäffer, Alejandro A., Yu, Yi-Kuo
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2647318/
https://ncbi.nlm.nih.gov/pubmed/19088134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn981
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