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The Basic Biology of BACE1: A Key Therapeutic Target for Alzheimer’s Disease

Alzheimer’s disease (AD) is an intractable, neurodegenerative disease that appears to be brought about by both genetic and non-genetic factors. The neuropathology associated with AD is complex, although amyloid plaques composed of the β-amyloid peptide (Aβ) are hallmark neuropathological lesions of...

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Detalhes bibliográficos
Main Authors: Cole, S.L, Vassar, R
Formato: Artigo
Idioma:Inglês
Publicado em: Bentham Science Publishers Ltd. 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2647160/
https://ncbi.nlm.nih.gov/pubmed/19415126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/138920207783769512
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