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QacR−Cation Recognition Is Mediated by a Redundancy of Residues Capable of Charge Neutralization†
[Image: see text] The Staphylococcus aureus multidrug binding protein QacR binds to a broad spectrum of structurally dissimilar cationic, lipophilic drugs. Our previous structural analyses suggested that five QacR glutamic acid residues are critical for charge neutralization and specification of cer...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Chemical Society
2008
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| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2646753/ https://ncbi.nlm.nih.gov/pubmed/18616285 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi8008246 |
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