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Analysis of Tryptophan Residues in the Staphylococcal Multidrug Transporter QacA Reveals Long-Distance Functional Associations of Residues on Opposite Sides of the Membrane

Tryptophan residues can possess a multitude of functions within a multidrug transport protein, e.g., mediating interactions with substrates or distal parts of the protein, or fulfilling a structural requirement, such as guiding the depth of membrane insertion. In this study, the nine tryptophan resi...

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Detalhes bibliográficos
Main Authors: Hassan, Karl A., Souhani, Talal, Skurray, Ronald A., Brown, Melissa H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2293199/
https://ncbi.nlm.nih.gov/pubmed/18223078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01864-07
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