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Similar Membrane Affinity of Mono- and Di-S-acylated Ras Membrane Anchors: A New Twist in the Role of Protein Lipidation

[Image: see text] The functionally required membrane attachment of Ras is achieved through an invariant isoprenylation of a C-terminal Cys, supplemented by further lipid modification of adjacent Cys residues by one (N-ras) or two (H-ras) palmitoyls. However, whether the triply lipidated membrane anc...

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Autori principali: Gorfe, Alemayehu A., McCammon, J. Andrew
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Chemical Society 2008
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2646725/
https://ncbi.nlm.nih.gov/pubmed/18761454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja805110q
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