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Reversible Effects of Peptide Concentration and Lipid Composition on H-Ras Lipid Anchor Clustering

Dynamic clusters of lipid-anchored Ras proteins are important for high-fidelity signal transduction in cells. The average size of Ras nanoclusters was reported to be independent of protein expression levels, and cholesterol depletion is commonly used to test the raft-preference of nanoclusters. Howe...

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Bibliographic Details
Published in:Biophys J
Main Authors: Lin, Xubo, Li, Zhenlong, Gorfe, Alemayehu A.
Format: Artigo
Language:Inglês
Published: The Biophysical Society 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4699922/
https://ncbi.nlm.nih.gov/pubmed/26682805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.11.009
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