DcpS as a Therapeutic Target for Spinal Muscular Atrophy

Spinal muscular atrophy (SMA) is caused by deletion or mutation of both copies of the SMN1 gene which produces an essential protein known as SMN. The severity of SMA is modified by variable copy number of a second gene, SMN2 that produces an mRNA that is incorrectly spliced with deletion of the last...

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Hlavní autoři: Singh, Jasbir, Salcius, Michael, Liu, Shin-Wu, Staker, Bart L., Mishra, Rama, Thurmond, John, Michaud, Gregory, Mattoon, Dawn R., Printen, John, Pollok, Brian A., Kiledjian, Megerditch, Christensen, Jeffery, Stewart, Lance, Jarecki, Jill, Bjornsson, Jon Mar, Gurney, Mark E
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2646632/
https://ncbi.nlm.nih.gov/pubmed/18839960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb800120t
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