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Suppression of Gonadotropins and Estradiol in Premenopausal Women by Oral Administration of the Nonpeptide Gonadotropin-Releasing Hormone Antagonist Elagolix

Context: Parenteral administration of peptide GnRH analogs is widely employed for treatment of endometriosis and fibroids and in assisted-reproductive therapy protocols. Elagolix is a novel, orally available nonpeptide GnRH antagonist. Objective: Our objective was to evaluate the safety, pharmacokin...

詳細記述

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書誌詳細
主要な著者: Struthers, R. Scott, Nicholls, Andrew J., Grundy, John, Chen, Takung, Jimenez, Roland, Yen, Samuel S. C., Bozigian, Haig P.
フォーマット: Artigo
言語:Inglês
出版事項: The Endocrine Society 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2646513/
https://ncbi.nlm.nih.gov/pubmed/19033369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2008-1695
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